S. Langer, Jr.
Langer revolutionized biomedical technology through the development
of a controlled drug delivery system.
was born in Albany, New York. After earning his doctorate at MIT
in 1974, he began developing a system for delivering inhibitors
to cancerous tumors. Langer discovered a way to control the delivery
of large molecule drugs by using both nondegradable and biodegradable
polymers to engineer synthetic materials that allow for precisely
timed chemical release.
made numerous improvements on his controlled delivery system.
Designing a chemotherapy wafer for the treatment of brain cancer,
he was able to administer slow releasing cancer-killing medication
directly where the cancerous tumor had been removed. He also pioneered
a variety of remotely controlled drug delivery systems that vary
the amount of drug released through electric impulse, ultrasound,
and magnetic field.
of over 300 U.S. and foreign patents, Langer's controlled drug
delivery innovations are the basis of a multibillion dollar industry
in the United States. An Institute Professor at the Massachusetts
Institute of Technology, Langer was recognized in 1998 with the
Lemelson-MIT Prize, being cited as one of history's most prolific
inventors in medicine.
Vinton G. Cerf
Robert E. Kahn
Robert W. Gore
Richard M. Hoe
John H. Thomas